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Zoloft is a strong antidepressant. The active substance – sertraline just helps to fulfill this function. With the normal functioning of the nervous system, it is produced by a neural tissue and improves the conduct of nerve impulses. So there is a state of depression. A longer time of serotonin in the free state provokes its enhanced production and, as a consequence, nerve conduction improves. They can also have different symptomatic manifestations.

Zoloft side effect.

Emotional lability, euphoria, hallucinations, paranoid reactions, somnambulism, withdrawal syndrome, edema, bronchospasm, cough, dyspnea, dysphagia, irritation of the mucous membrane of the gastrointestinal tract, hypersalivation, glossitis, gingival hypertrophy, ulcerative stomatitis, arthralgia, dysmenorrhea, breast enlargement and soreness, anemia, lymphadenopathy, dysuria, disturbances of consciousness, ataxia, discoordination, hyper- and paresthesia, hyperkinesia, hypo- and dyskinesia, generalized convulsions, migraine, mydriasis, nystagmus, dizziness, headache, arterial hypertension or hypotension, tachycardia, collaptoid states, ptosis, hyporeflexia, sleep disturbance, aggressiveness, amnesia, apathy, depersonalization, allergic reactions.


There are no controlled results of the use of sertraline in pregnant women, therefore Zoloft can be prescribedduring pregnancy only if the expected benefit for the mother exceeds the potential risk for the fetus. Female reproductive age during treatment with sertraline should use effective methods of contraception. Sertraline is found in breast milk, and therefore the use of Zoloft in the lactation period is not recommended. In this case there are no reliable data on the safety of its application. If the purpose of the drug is necessary, then breastfeeding should be discontinued.

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Active substance for Lasix: Furosemide.
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